Professor Monica Diluca



Academic career
  • Laurea cum laude in Chemistry and Pharmacology Technology, University of Milano Faculty of Pharmacy - 110 lode/110 (1986)
  • PhD in "Pharmacology", University of Milano, Faculty of Pharmacy(1992)
  • PhD in Medical Sciences, University of Utrecht, School of Medicine(1993)
Professional experience
  • Vice - Rector for International Strategies, University of Milano: 2014 - today
  • Director of NeuroNest (University of Milano Centre of Neuroscience): 2014 - today
  • Head of Laboratory of Pharmacology of Neurodegeneration - DiSFeB Univ. of Milano
  • Full Professor of Pharmacology - University of Milano (2011 - present)
  • Associated Professor of Pharmacology - University of Milano (2000 - 2011)
  • Assistant professor, University of Milano Institute of Pharmacological Sciences (1995 - 2000)
Honours and awards
  • Doctor Honoris Causa University of Bordeaux (Oct 2019)
  • Laurea Honoris Causa Faculty of Medicine and Pharmacy, University of Mons (Belgium) (March 2017)
  • EMBO membership (2017)
  • Visiting professor at Liaoning Normal University, Dalien (2017)
  • “Otto Creutzfeldt Lecture”, 12th Goettingen Meeting of the German Neuroscience Society (2017)
  • ENCP Media Award (2013)
  • EDAB, European Dana Alliance Invited Member (2008)
  • Award for Neuroscience - Italian Society for Neuroscience (1997)
  • Award of the University of Milano Faculty of Pharmacy for "Studies on neuronal plasticity" (1994)
Learned Societies and Boards
  • EBC - European Brain Council (Member of Advisory Board: 2003-2006; Vice-President: 2010-2016; President: 2017- 2021)
  • IBRO, International Brain Organization (Chair of Western Europe Regional Committee: 2006-2010; Executive Director Inter-Regional activities, 2010-2014)
  • FENS - Federation of European Neuroscience Societies (Member of Scientific Programme Committee: 1996-2000; General Secretary: 2000-2006; Member of Board Programme of European Neuroscience Schools, PENS: 2006-2010; President 2014 - 2016)
  • Federation of European Neuroscience Societies Trust (President: 2006 – 2014)
  • SfN - Society for Neuroscience (Member of Women in Neuroscience Committee: 2007 - 2010; Member of Professional Development Committee: 2009 - 2012)
  • SINDEM - Società Italiana Neurologia delle Demenze (Board Member: 2012 - today)
  • SINEG - Società Italiana di Neurogeriatria (Board Member 2005-2009)
  • SINS - Società Italiana di Neuroscienze (Board Member 2001-2005)
  • SIF - Società Italiana di Farmacologia (Coordinator for "Regione Lombardia": 2007-present; Coordinator Group of Neurodegenerative Diseases: 2012; Board Member: 2013-2017)
  • Board of Full Professors of Pharmacology, Secretary and Treasurer, 2018
  • Italian Interdisciplinary Network on Alzheimer Disease, ITINAD (Scientific Secretary: 1998-2001; Vice President: 2001-2009)
  • University of Milano - National Coordinator Working Group CRUI H2020: 2012
  • University of Milano - delegate at "The League of European Research Universities" (LERU) - 2015 - today
Revision Panels

Professor Monica diLuca has served as member of several panels for the European Commision framework programmes 7 and H2020.
In addition:

  • 2000-2004 International Panel of Experts for Neuroscience - FCT Fundação para a Ciêinca e a Tecnologia, Ministério da Ciência e da Tecnologia – Portugal
  • 2006 - Advisor for the BBSRC (Biotechnology and biology Research Council) panel, UK
  • 2009 -2010 AERES, Agence de l'Evaluation de la Recherche et des Etablissements d'Enseignement Supérieur, French Research Agency
  • 2011 - Member of Visiting Committee KU Leuven
  • 2014-2016 - Eric Kandel Young Neuroscientists Prize
  • 2012-2016 - FENS EJN Awards Evaluation Committee
  • 2014 -2016 - IBRO-Kemali Prize
  • 2014-2018 - DANA awards
  • 2019-2021 - Member of Lundbeckfonden's Grants & Prizes panel
  • 2019-2022 - Member of DZNE Senate
  • 2019-2021 - SfN Julius Axelrod Prize Selection Committee
Organizational activities
  • 2017 - 6th European Synapse Meeting - Milano, 4/6 December
  • 2017 - Cajal Advanced Programme in Neuroscience: Synapse Course - Bordeaux, 02/21 July
  • 2016 - 10th FENS Forum, Copenhagen
  • 2014 - 9th FENS Forum – Milan
  • 2013 - SIF (Società Italiana di Farmacologia) - "Alzheimer Disease: which are the challenges we need to face?" From basic mechanisms to genetic and translational aspects - Milan
  • 2011 - "The Synapse: From physiology to pathology" - Stresa, 4-7 September, Satellite of International Society of Neuroschemistry" (ISN)
  • 2006 - FENS Forum - Vienna, 11-15 July
  • 2004 - Vice-Chair of the EURESCO conference on Learning and Memory - Obernai
  • 2004 - FENS Forum - Paris, 13-17 July
  • 2002 - FENS Forum - Lisbona, 10-4 July
  • 1999 - FENS Summer School on "Neurodegeneration and Regeneration: from basic to disease" - Elba
  • 1998 - Official Satellite of the European Neuroscience Forum "Synaptic plasticity learning and memory" - Berlin
  • 1998 - "Federation of European Neuroscience Societies (FENS) Forum " - Berlin
  • 1997 - Elba Summer School of Neuroscience (ENA): "Degeneration and regeneration in the Nervous System: mechanisms and disease"
Editorial Activities
  • 1998 - 2004 Editor: Neuroscience Research Communication
  • 2000 - 2006 Member of Publication Committee: European J. Neuroscience
  • 2006 - 2016 Editorial Board: Neural Plasticity
  • 2007 - Editorial Board: Pharmacological research
  • 2007 - Editorial Board: European J Pharmacology
  • 2009 - Review Editor: Frontiers in Synaptic Neuroscience
  • 2009 - 2017 Faculty 100 – Member Faculty Medicine – Alzheimer
  • 2011 - 2016 Editorial Board: Synapse
  • 2016 - Editorial Board: Neuroscience
Funding
  • Italian Ministry of University and Research (PRIN2015, PRIN2010-11, FIRB2011, PRIN2008, FIRB2003)
  • Italian Ministry of Health (Min.San. 2016, 2010, 2008, 2004, 2002, 2000)
  • CNR (1999, 1998, 1995)
  • JPco-fuND, STAD project 2016
  • European Commission (H2020-MSCA-ITN-2015; FP7 SymBAD ITN; FP7 REPLACES Collaborative project; FP7 cPADS, IAPP project, FP6 SynScaff Collaborative projects)
  • Foundations (Cariplo, IPSEN, Telethon, AlzOrg)
Patents
  • European patent application EP 13196710.1 - 1456 (ADAM10 inhibition to treat Fragile X syndrome), registered on 11/12/2013.
Research interests

Monica DiLuca is the author of over 180 articles published in peer reviewed journals. Over the last ten years she has given over 60 invited lectures at international meetings or at universities in Europe, North America and Asia.

Monica DiLuca's primary research interest is related to brain and synaptic plasticity both in physiological and pathological conditions, with the primary aim to apply her basic findings to the cure of neurodegenerative diseases as Alzheimer and Parkinson Disease. Monica DiLuca's group has made significant contributions to the understanding of the molecular mechanisms regulating the composition, the structural organization and the dynamic of the glutamatergic synapse. Her group has identified a key role of glutamatergic synapse components in neurodegenerative diseases, particularly focusing on composition of NMDA receptors. Notably, Monica DiLuca's group identified pillars of amyloid cascade in the core of the glutamatergic synapse. These discoveries have radically changed the understanding of Alzheimer disease pathogenesis, with far reaching ramifications for neuronal plasticity and memory as well as neuroprotection. These findings open new avenues to identify novel molecules targeting early synaptic dysfunction for pharmacological interventions in the still unresolved need of neurodegenerative diseases' treatment.